Yes. Cemair, Airlink, FlySafair, and Mango Airlines are all flying domestic routes in South Africa and domestic flights are permitted across all provinces (for all purposes, business and leisure).
Passengers should arrive at the airport at least two hours before a domestic flight to ensure enough time is allocated for screening and operational procedures. Only ticket holders will be admitted to the terminal building. Security staff will check tickets and temperatures at the entrance and persons with a temperature higher than 38 degrees will not be permitted to enter. Masks must be worn and social distancing of 1,5 metres must be adhered to at all times in the airport.
Travellers should complete the domestic screening questionnaire from the Department of Health, to be submitted before their flight.